Central Carbon Metabolism

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Description

Quantification of glucose, sugar phosphates, CoAs, enzyme co-factors, TCA cycle carboxylic acids, phosphocarboxylic acids and major nucleotides involved in Central Carbon Metabolism (CCM) and glucosamine metabolism by UPLC-MRM/MS

Quantitative

Absolute

Platform Available

UPLC-MRM/MS

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Name	HMDB ID	Super Class	Class
6-Phosphogluconate (6PG)
6-Phosphogluconone
Deoxyribose 1-phosphate
Dihydroxyacetone-P (DHAP)
FAD
FMN
Fructose-1-P
Fructose-1,6-bisP
Glucosamine 6-P
Glucose-1,6-bisP
Glucose-6-P
Glycerate-1,3-bisP
Glycerate-2,3-bisP
Glycerate-2P
Glycerate-3P
Glycerol-3P
α-Hydroxyglutaric acid
α-Ketogluteric acid
β-Hydroxybutyric acid
Mannose-6-P
N-Acetyl-glucosamine 1-P
Phosphoenolpyruvate (PEP)
Ribose-1-P
Ribose-1,5-bisP
Ribulose-1,5-bisP
Sedoheptulose-7P
Shikimate-3P
UDP-N-acetylglucosamine (UDP-GlcNAc)
Xybulose-5P
Acetoacetyl-CoA		Lipids and lipid-like molecules	Fatty Acyls
Acetyl-CoA		Lipids and lipid-like molecules	Fatty Acyls
Citraconic acid		Lipids and lipid-like molecules	Lipids and lipid-like molecules
Citramalic acid	HMDB0176421	Lipids and lipid-like molecules	Fatty Acyls
Malonyl-CoA		Lipids and lipid-like molecules	Fatty Acyls
Succinyl-CoA		Lipids and lipid-like molecules	Fatty Acyls
ADP	HMDB01341	Nucleosides, nucleotides, and analogues	Purine nucleotides
ADP-glucose		Nucleosides, nucleotides, and analogues	Purine nucleotides
AMP	HMDB00045	Nucleosides, nucleotides, and analogues	Purine nucleotides
ATP	HMDB00538	Nucleosides, nucleotides, and analogues	Purine nucleotides
cAMP		Nucleosides, nucleotides, and analogues	Purine nucleotides
cGMP		Nucleosides, nucleotides, and analogues	Purine nucleotides
GDP		Nucleosides, nucleotides, and analogues	Purine nucleotides
GDP-fucose		Nucleosides, nucleotides, and analogues	Purine nucleotides
GDP-glucose		Nucleosides, nucleotides, and analogues	Purine nucleotides
GMP		Nucleosides, nucleotides, and analogues	Purine nucleotides
GTP	HMDB01273	Nucleosides, nucleotides, and analogues	Purine nucleotides
HS-CoA		Nucleosides, nucleotides, and analogues	Purine nucleotides
NAD+		Nucleosides, nucleotides, and analogues	Nucleosides, nucleotides, and analogues
NADH		Nucleosides, nucleotides, and analogues	Nucleosides, nucleotides, and analogues
NADP+		Nucleosides, nucleotides, and analogues	Nucleosides, nucleotides, and analogues
NADPH		Nucleosides, nucleotides, and analogues	Nucleosides, nucleotides, and analogues
UDP	HMDB0062654	Nucleosides, nucleotides, and analogues	Pyrimidine nucleotides
UDP-glucose	HMDB00286	Nucleosides, nucleotides, and analogues	Pyrimidine nucleotides
UMP	HMDB00288	Nucleosides, nucleotides, and analogues	Pyrimidine nucleotides
UTP		Nucleosides, nucleotides, and analogues	Pyrimidine nucleotides
Acetoacetic acid	HMDB0000060	Organic acids and derivatives	Keto acids and derivatives
Acetoacetic acid	HMDB0000060	Organic acids and derivatives	Keto acids and derivatives
Aconitic acid	HMDB0164614	Organic acids and derivatives	Carboxylic acids and derivatives
Citric acid	HMDB0000094	Organic acids and derivatives	Carboxylic acids and derivatives
Fumaric acid	HMDB00134	Organic acids and derivatives	Carboxylic acids and derivatives
Glycolic acid	HMDB0000115	Organic acids and derivatives	Hydroxy acids and derivatives
Isocitric acid	HMDB0000193	Organic acids and derivatives	Carboxylic acids and derivatives
Lactic acid	HMDB0041561	Organic acids and derivatives	Hydroxy acids and derivatives
Malic acid	HMDB0167333	Organic acids and derivatives	Hydroxy acids and derivatives
Methylcitric acid		Organic acids and derivatives	Carboxylic acids and derivatives
Methylcitric acid		Organic acids and derivatives	Carboxylic acids and derivatives
Oxaloacetic acid	HMDB00223	Organic acids and derivatives	Keto acids and derivatives
Phosphocreatine		Organic acids and derivatives	Carboxylic acids and derivatives
Pyruvic acid	HMDB0141776	Organic acids and derivatives	Keto acids and derivatives
Succinic acid	HMDB0000254	Organic acids and derivatives	Carboxylic acids and derivatives
Erythrose-4-P		Organic oxygen compounds	Organooxygen compounds
Fructose-6-P		Organic oxygen compounds	Organooxygen compounds
Glucaric acid		Organic oxygen compounds	Organooxygen compounds
Gluconic acid		Organic oxygen compounds	Organooxygen compounds
Glucose	HMDB0000516	Organic oxygen compounds	Organooxygen compounds
Glucose-1-P		Organic oxygen compounds	Organooxygen compounds
Glyceraldehyde-3-P		Organic oxygen compounds	Organooxygen compounds
Glyceric acid	HMDB0160653	Organic oxygen compounds	Organooxygen compounds
N-Acetyl-glucosamine		Organic oxygen compounds	Organooxygen compounds
Ribose	HMDB0000283	Organic oxygen compounds	Organooxygen compounds
Ribose-5-P		Organic oxygen compounds	Organooxygen compounds
Ribulose-5-P		Organic oxygen compounds	Organooxygen compounds