Folate Cycle /Methionine Cycle/Transsulfuration Pathway Assay

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Description

Quantification of metabolites in folate cycle, methione cycle, choline metabolism, transsulfuration pathway and vitamin co-factors by LC-MS.

Quantitative

Absolute

Platform Available

UPLC-MRM/MS

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Name	HMDB ID	Super Class	Class
Acetyl choline
Dihydrofolate (DHF)
Glutathione oxidized (GSSG)
Glutathione reduced (GSH)
Tetrahydrofolate (THF)
Vitain B2
dcSAM		Nucleosides, nucleotides, and analogues	5'-deoxyribonucleosides
SAH		Nucleosides, nucleotides, and analogues	5'-deoxyribonucleosides
SAM		Nucleosides, nucleotides, and analogues	5'-deoxyribonucleosides
Betaine	HMDB0000043	Organic acids and derivatives	Carboxylic acids and derivatives
Cystathionine	HMDB00099	Organic acids and derivatives	Carboxylic acids and derivatives
Cysteine	HMDB00574	Organic acids and derivatives	Carboxylic acids and derivatives
Cystine	HMDB0000192	Organic acids and derivatives	Carboxylic acids and derivatives
Folate		Organic acids and derivatives	Carboxylic acids and derivatives
Glycine	HMDB0000123	Organic acids and derivatives	Carboxylic acids and derivatives
Homocysteine	HMDB00742	Organic acids and derivatives	Carboxylic acids and derivatives
Homocysteine	HMDB00742	Organic acids and derivatives	Carboxylic acids and derivatives
Homoserine	HMDB0000719	Organic acids and derivatives	Carboxylic acids and derivatives
Hypotaurine		Organic acids and derivatives	Sulfinic acids and derivatives
Methionine	HMDB0000696	Organic acids and derivatives	Carboxylic acids and derivatives
Serine	HMDB0001264	Organic acids and derivatives	Carboxylic acids and derivatives
Taurine	HMDB0000251	Organic acids and derivatives	Organic sulfonic acids and derivatives
Choline	HMDB0000097	Organic nitrogen compounds	Organonitrogen compounds
5-Methyl THF		Organoheterocyclic compounds	Pteridines and derivatives
Vitamin B12		Organoheterocyclic compounds	Organoheterocyclic compounds
Vitamin B6		Organoheterocyclic compounds	Pyridines and derivatives